Aim A regional analysis was used to explore the influence of river regulation on the dominance of non-native, invasive shrubs and trees. We addressed the following questions: (1) How do large dams affect hydrological parameters that influence riparian vegetation? (2) How do flow regimes affect the dominance of non-native woody species? (3) How do changes in flow regimes affect the dominance of non-native woody species? Location South-western USA. Methods We sampled the canopy cover of woody species on 179 point bars along seven non-dammed and thirteen dammed river segments. Wilcoxon rank sum tests were used to determine differences between flow parameters in dammed and non-dammed rivers. We used correlation analyses and generalized [...]