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Biosynthetic pathway of mycosporines (mycosporine-like amino acids) in the cyanobacterium Chlorogloeopsis sp. strain PCC 6912

Citation

Ferran Garcia-Pichel, and Anne Portwich, Biosynthetic pathway of mycosporines (mycosporine-like amino acids) in the cyanobacterium Chlorogloeopsis sp. strain PCC 6912: .

Summary

We used metabolic inhibitors and radiolabelled tracers to investigate the biosynthetic pathway for mycosporines (mycosporine-like amino acids) in the facultatively heterotrophic cyanobacterium (blue-green alga) Chlorogloeopsis sp. strain PCC 6912. 14C-pyruvate was taken up and resulted in labelling of the core cyclohexenone, whereas feeding with 14C-acetate did not label cyclohexenone, in spite of strong cellular uptake. In addition, mycosporine synthesis was depressed in the presence of externally administered tyrosine (5 mM), a known feedback inhibitor of the shikimic acid pathway in cyanobacteria. We thus conclude that the mycosporine core cyclohexenone in cyanobacteria is derived from the shikimate pathway, as has been suggested [...]

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  • Upper Colorado River Basin

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From Source - Mendeley RIS export <br> On - Tue May 10 11:13:07 CDT 2011

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Title Citation Biosynthetic pathway of mycosporines (mycosporine-like amino acids) in the cyanobacterium Chlorogloeopsis sp. strain PCC 6912

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