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Relation among cytochrome P450, Ah-active PCB congeners and dioxin equivalents in pipping black- crowned night-heron embryos

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Relation among cytochrome P450, Ah-active PCB congeners and dioxin equivalents in pipping black- crowned night-heron embryos; 1994; Article; Journal; Environmental Toxicology and Chemistry; Rattner, B. A.; Hatfield, J. S.; Melancon, M. J.; Custer, T. W.; Tillitt, D. E.

Summary

Pipping black-crowned night-heron (Nycticorax nycticorax) embryos were collected from a relatively uncontaminated site (next to Chincoteague National Wildlife Refuge, VA) and three polluted sites (Cat Island, Green Bay, Lake Michigan, WI; Bair Island, San Francisco Bay, CA; West Marin Island, San Francisco Bay, CA). Hepatic cytochrome P450-associated monooxygenases and cytochrome P450 proteins, induced up to 85- fold relative to the reference site, were associated with concentrations of total polychlorinated biphenyls (PCBs) and 11 PCB congeners that are presumed to express toxicity through the arylhydrocarbon (Ah) receptor. Multiple regression revealed that up to 86% of the variation of cytochrome P450 measurements was accounted for [...]

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  • Upper Midwest Environmental Sciences Center (UMESC)

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Type Scheme Key
local-index unknown 1003190
local-pk unknown 1003190
series unknown Environmental Toxicology and Chemistry

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journalEnvironmental Toxicology and Chemistry
parts
typevolume
value13
typeissue
value11
languageEnglish
citationTypeArticle

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