Climate and land use affect water quantity and quality; however, the complex relations of climate and land use regarding flow and instream nutrient levels have yet to be elucidated. This study aims to assess the hydrologic effects of different land-use and climatic regimes in the Lower Great Miami River Basin. The modelling results from BASINS showed that, as expected, agricultural lands and the wettest scenario yielded the highest amount of streamflow, fecal coliform, and nutrient loadings. But, it was the dry scenario (+2°C, -20% precipitation of the current average climatic conditions in SW Ohio), instead of the driest scenario (+4°C, -20% precipitation), that produced the highest daily nutrient concentrations. When the future land-use [...]