Assessing the impact of predators on a prey population is inherently challenging, a fortiori in remote ecosystems. With this thesis, I studied the interactions between a recently declining Dall sheep (Ovis dalli dalli ) population and two predators: grizzly bears (Ursus arctos ) and wolves (Canis lupus ), in the secluded Northern Richardson Mountains, Canada. After reviewing the status of this Dall sheep population, I investigated its interactions with grizzly bears and wolves -mostly the indirect effects of predation; using satellite telemetry, habitat utilization analyses, δ 13 C and δ15 N stable isotopes, behavioural observations, and the documentation of Gwich'in and Inuvialuit Traditional Ecological Knowledge (TEK). At the spatial [...]