Skip to main content
USGS - science for a changing world

Metabolomics: Developing a chemical specific fingerprint

Dates

Publication Date
Start Date
2015-12-10
End Date
2016-02-10

Citation

Joel Putnam, 2017, Metabolomics: Developing a chemical specific fingerprint: U.S. Geological Survey data release, http://dx.doi.org/10.5066/F7KH0KGC

Summary

We combine cell assays and metabolomics to create a powerful tool, which emerges to elevate the identification of new control chemicals. We combined the use of bigheaded carp fry cell line with metabolite profiling to describe the dose response to thiram. Thiram is a registered pesticide commonly used as a fungicide in the field or as a seed protectant and is known to be toxic to fish. Seven concentrations of thiram were used to dose bighead carp fry cells and silver carp fry cells. We identified 700 metabolomic markers and 41 of those markers exhibited a dose response to thiram in the bighead carp fry cells. We identified 1590 metabolomic markers with 205 of those markers exhibited a dose response to thiram in the silver carp fry [...]

Contacts

Point of Contact :
Joel Putnam
Originator :
Joel Putnam
Metadata Contact :
Joel G Putnam
Distributor :
GS ScienceBase

Attached Files

Click on title to download individual files attached to this item.

BHC supplement - Table 1.csv 372.22 KB
SVC supplement - Table 2.csv 498.55 KB
Metabolomics_Developing_a_chemical_specific_fingerprint.xml
Original FGDC Metadata

View
182.8 KB

Purpose

The data was collected using a high performance liquid chromatography unit linked with a time of flight mass spectrometer (HPLC-QTOF). Further statistical analysis of this data may provide answers to additional biological research.

Communities

  • Upper Midwest Environmental Sciences Center (UMESC)

Tags

Provenance

Data source
Input directly

Item Actions

View Item as ...

Save Item as ...

View Item...