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Seasonal changes in cortisol sensitivity and glucocorticoid receptor affinity and number in leukocytes of coho salmon

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Alec G. Maule, Carl B. Schreck, and Cameron Sharpe, 1993, Seasonal changes in cortisol sensitivity and glucocorticoid receptor affinity and number in leukocytes of coho salmon: Fish Physiology and Biochemistry, v. 10, iss. 6.

Summary

To determine if there were organ-specific changes in immune responses or immune-endocrine interaction, we monitored in vitro immune response, cortisol sensitivity and number and affinity of glucocorticoid receptors (GR) in leukocytes from freshwater-adapted juvenile coho salmon (Oncorhynchus kisutch) during the physiological changes that prepare them to enter the marine environment. During this period, absolute immune response declined, but splenic leukocytes generated more antibody-producing cells than did cells from anterior kidney. Splenic leukocytes were initially more sensitive to the suppressive effects of cortisol and had fewer GR than leukocytes from the anterior kidney. Leukocytes from the anterior kidney were initially insensitive [...]

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Type Scheme Key
local-index unknown 70180492
local-pk unknown 70180492
doi http://www.loc.gov/standards/mods/mods-outline-3-5.html#identifier doi:10.1007/BF00004605
series unknown Fish Physiology and Biochemistry

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journalFish Physiology and Biochemistry
parts
typevolume
value10
typeissue
value6
languageEnglish
citationTypeArticle

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