This data release contains water depth, depth-averaged water velocity, and river stationing (based on 2012 ortho-imagery) in select locations in the Lower San Joaquin River, California, 2011-2014. Between 2011 and 2014, the U.S. Geological Survey, in cooperation with the U.S. Fish and Wildlife Service (USFWS), collected approximately 105 channel cross-sections and multiple longitudinal profiles, which comprised of nearly 150,000 streamflow-velocity measurements and 246,000 water-depth measurements in various reaches and subreaches of the Lower San Joaquin River between Orestimba Creek and Sturgeon Bend. The data collection locations in the Lower San Joaquin River were selected based on discussions with USFWS to overlap with their sturgeon monitoring sites and areas that may provide beneficial spawning habitat (such as adjacent to gravel bars or known deep scour holes, etc.). An acoustic Doppler current profiler (ADCP) was primarily used to collect the depth and velocity data, however, in 2011 a multibeam sonar was used to map bathymetry in some areas.