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Investigation of pharmaceuticals in water, fish, and ospreys nesting in Delaware River and Bay


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Rattner, B.A. and Bean, T.G., 2017, Investigation of pharmaceuticals in water, fish, and ospreys nesting in Delaware River and Bay: U.S. Geological Survey data release,


Exposure of wildlife to Active Pharmaceutical Ingredients (APIs) is likely to occur but evidence of hazard and risk is limited. One exposure pathway that has received attention is trophic transfer of APIs in a water-fish-osprey food chain. Samples of water, fish plasma and osprey plasma were collected from Delaware River and Bay, and analyzed for 21 APIs. Only 2 of 21 analytes exceeded Method Detection Limits (MDL) in osprey plasma (acetaminophen and diclofenac) with plasma levels typically 2-3 orders of magnitude below human therapeutic concentrations (HTC). We built upon a screening level model used to predict osprey exposure to APIs in Chesapeake Bay and evaluated whether exposure levels could have been predicted in Delaware Bay [...]


Point of Contact :
Barnett A Rattner
Originator :
Barnett A Rattner, Thomas G Bean
Metadata Contact :
Barnett A Rattner
publisher :
U.S. Geological Survey
Distributor :
GS ScienceBase
USGS Mission Area :
Environmental Health
SDC Data Owner :
Patuxent Wildlife Research Center

Attached Files

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Explanation of metadata.txt
“Explanation of metadata”
5.19 KB
Graphical Abstract Bean et al 2017 DE Bay APIs.jpg
“Graphical Abstract”
thumbnail 229.95 KB
MRM compound instrument parameters table for Delaware Bay.pdf
“MRM Compound Instrument Parameters Table”
279.71 KB
Additive 10% MDL.xls
“Additive 10% MDL”
14.28 KB
Additive MDL.xls
“Additive MDL”
14.17 KB
Fish plasma.xls
“Fish plasma”
15.04 KB
Fish species eaten by osprey.xls
“Fish species eaten by osprey”
9.43 KB
“Method Detection Limits (MDLs)”
12.92 KB
Osprey plasma.xls
“Osprey plasma”
12.05 KB
“Osprey Predicted”
13.11 KB
Predictive framework.xls
“Predictive framework”
35.5 KB
37.5 KB


Data collected as part of a large ecotoxicology study to assess concentrations, geographic gradients and temporal trends in contaminant exposure of ospreys nesting in Delaware River and Bay
Graphical Abstract
Graphical Abstract



  • Patuxent Wildlife Research Center
  • USGS Data Release Products



Additional Information


Type Scheme Key
DOI doi:10.5066/F7KP80MW

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