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The effect of polychlorinated naphthalenes and tributyltin on the occurrence of aberrant nuclei in erythroid cells of medaka

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Melaniya G. Talykina, Diana M. Papoulias, J. Alan Allert, Y.U. Izyuov, Sergio A. Villalobos, John P. Giesy, and Donald E. Tillitt, 2003, The effect of polychlorinated naphthalenes and tributyltin on the occurrence of aberrant nuclei in erythroid cells of medaka: Environmental Sciences, v. 10, iss. 6.

Summary

The micronucleus test using erythrocytes of the peripheral blood of fish is often conducted to evaluate the genotoxic effects of pollutants under experimental and natural conditions. This report presents information on the production of micronuclei and other nuclear anomalies in erythrocytes of medaka (Oryzias latipes) exposed to three polychlorinated naphthalene (PCN) formulations (Halowaxes 1014, 1031 and 1051) or tributyltin (TBT). Three types of deviation in the morphology of interphase nuclei were observed in medaka erythrocytes: micronuclei, nuclei fragmented into two equal or unequal parts, and nuclei at different stages of invagination. The number of erythrocytes with nuclear anomalies typically increased after chemical exposure. [...]

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Type Scheme Key
local-index unknown 70188616
local-pk unknown 70188616
series unknown Environmental Sciences

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journalEnvironmental Sciences
parts
typevolume
value10
typeissue
value6
languageEnglish
citationTypeArticle

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