The Northeast Regional Conservation Framework Workshop, held in June 2011, provided an opportunity to step back and synthesize the results of many projects that have been completed or are underway through the Northeast Association of Fish and Wildlife Agencies Regional Conservation Needs (RCN) program and Landscape Conservation Cooperatives (LCCs). The workshop also helped partners determine how these projects might fit into a common regional conservation framework and identify the greatest needs for future work. By fostering information sharing and discussions among regional conservation experts, the workshop sought to clarify the “big picture” of conservation, illuminate how existing efforts complement each other, and identify key roles for each of the partners to play in the future. These activities all contributed to the overarching goal of achieving more effective and efficient conservation in the Northeast region. The workshop results are guiding the development of shared science capacity in the Northeast.