The aquifer saturated thickness product is a per-pixel (250 square-meters) model representation of the combined fluid and soil matrix volume of water available in a given area, represented in units of linear feet. The prediction of available water is made using a network of over 9,300 monitoring wells located throughout the High Plains aquifer region. These wells are part of an annually updated long-term water-level monitoring study being conducted by United States Geological Survey hydrologists and other partners (https://ne.water.usgs.gov/ogw/hpwlms/). We used the source well depth-to-water data, as well as information on the base elevation of the aquifer (USGS Report : ofr98-393), surface elevation (NED-DEM), and spatial terms (4th-order polynomial trend interpolation of latitude and longitude) to build a generalized linear model of saturated thickness for the High Plains region, following earlier modeling work of V. McGuire (https://goo.gl/bfXgKY). The source code for this analysis is published in the R package ‘Ogallala’ (https://github.com/PLJV/Ogallala).