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Pesticides in small volume plasma samples

Dates

Publication Date
Start Date
2020-01-01
End Date
2022-01-01

Citation

Gross, M.S., and Hladik, M.L., 2024, Pesticides in Small Volume Plasma Samples, U.S. Geological Survey data release, https://doi.org/10.5066/P9OTMSB0.

Summary

Pesticides are widely applied and can enter the environment, potentially effecting non-target organisms. To better evaluate pesticide exposure using non-lethal techniques, a method was developed for the extraction of pesticides and their degradates from small (100 µL) volume plasma samples. Solid phase extraction was used for lipid removal after plasma samples were protein precipitated. Samples were analyzed with liquid chromatography and gas chromatography with tandem mass spectrometry. Samples were spiked at three different concentrations, low (25 ng/mL), medium (100 ng/mL), and high (250 ng/mL) and recoveries of 70 to 130% were achieved across all spike levels for 179, 180, and 183 of 210 target compounds were achieved, respectively; [...]

Contacts

Point of Contact :
Michelle L Hladik
Process Contact :
Michelle L Hladik
Originator :
Michael S Gross, Michelle L Hladik
Metadata Contact :
Michelle L Hladik
Publisher :
U.S. Geological Survey
Distributor :
U.S. Geological Survey - ScienceBase
SDC Data Owner :
California Water Science Center
USGS Mission Area :
Ecosystems

Attached Files

Click on title to download individual files attached to this item.

Plasma recoveries MDLs.csv
“recoveries and MDLs”
17.86 KB text/csv

Purpose

Method developed for the extraction and analysis of pesticides in small volume samples to better understand pesticide fate and exposure.

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Communities

  • USGS California Water Science Center
  • USGS Data Release Products

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Additional Information

Identifiers

Type Scheme Key
DOI https://www.sciencebase.gov/vocab/category/item/identifier doi:10.5066/P9OTMSB0

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