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This study examines the health impacts of recent heat waves statewide and for six subregions of California: the north and south coasts, the Central Valley, the Mojave Desert, southern deserts, and northern forests. By using canonical correlation analysis applied to daily maximum temperatures and morbidity data in the form of unscheduled hospitalizations from 1999 to 2009, 19 heat waves spanning 3–15 days in duration that had a significant impact on health were identified. On average, hospital admissions were found to increase by 7% on the peak heat-wave day, with a significant impact seen for several disease categories, including cardiovascular disease, respiratory disease, dehydration, acute renal failure, heat...