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This research examines the effects of climate change on the species composition of forests in the southern Great Lakes region in USA (Illinois, Indiana, and Ohio) by simultaneously addressing five key components necessary for realistic predictions of future forest composition. We simulated transient (1), species-level (2), forest response to climate change at a spatial scale that accounted for competitive effects (3), and regional site diversity (4), in the spatial configuration of forests within the regional landuse matrix (5). The JABOWA-II forest growth model was used to provide species-specific responses of 45 tree species to site conditions (e.g. climatic, edaphic) while accounting for competition for limited...