Histopathology of American Kestrels (Falco sparverius) Exposed to Two Brodifacoum Isomer Formulations with Differing Elimination Half-Lives

This dataset documents histopathological changes in liver, kidney, skeletal muscle and intestine of captive American kestrels (Falco sparverius) exposed to brodifacoum formulations with differing elimination half-lives in target rodents. The toxicity of two brodifacoum formulations with stereoisomers having markedly different elimination half-lives in rats (Formulation A containing the 2 least persistent stereoisomers, Formulation B containing the most persistent stereoisomer) were tested in a 7-day dietary feeding trial. Based on previous kestrel studies using commercially available brodifacoum, Formulations A and B were each provided at 3 dietary concentrations (0.05, 0.1 and 0.5 µg/g diet, 4 kestrels/dose level)...

Categories: Data; Tags: Anticoagulant, Environmental Health, USGS Eastern Ecological Science Center, Laurel, MD, USGS National Wildlife Health Center, Madison, Wisconsin, USA, USGS Science Data Catalog (SDC), All tags... Wildlife Disease, biota, birds, brodifacoum isomers, hazard, histopathology, non-target effects, risk, Fewer tags

Brodifacoum isomer formulation study

Body weight and weight change during course of study, estimates of food and brodifacoum consumption, observations of test birds during feeding trial and at necropsy, hematocrit, and prothrombin time

Categories: Data; Tags: Anticoagulant, Brodifacoum isomers, Environmental Health, Environmental Health, Hazard, All tags... Maryland, Non-target effects, Risk, USGS Science Data Catalog (SDC), biota, birds, Fewer tags