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Data from study assessing the utility of knowledgebase-leveraging of comprehensive environmental-contaminant-exposure datasets by comparing biological effects predicted on the basis of target chemical analyses with measured biological effects in corresponding split water samples.
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Human-use pharmaceutical compounds were analyzed at the U.S. Geological Survey, National Water Quality Laboratory, Denver, Colorado, in wadeable streams in 4 Regional Stream Quality Assessments: Northeast (NESQA), Southeast (SESQA), Pacific Northwest (PNSQA) and California (CSQA). Multiple (with few exceptions) samplings occurred at each site, during base flow, between 2014 and 2017. Sites were located in the headwaters of perennial, wadeable streams in urban and agricultural watersheds. Site selection and methodology for each assessment can be found in Van Meter and others (2015), Sheibley and others (2015), Van Meter and others (2017), Coles and others (2019), Van Meter and others (2016), Journey and others (2015),...
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This dataset presents the results of 475 unique organic compounds collected from 54 wadeable streams within the Southeastern, USA, collected within 10 weeks during 2014. Maximum and median exposure conditions were evaluated in relation to watershed characteristics and for potential biological effects. This dataset contains the summary statistics (maximum and median concentrations)of detected compounds, as well as a summary of quality-assurance (blanks and replicates) samples. Also included are the statistical summaries as related to analyte specific contaminant detection/concentration data and site-specific land-use matrices, spearman-rank correlations, and ToxCast evaluations.


    map background search result map search result map Concentrations of Pesticides, Pharmaceuticals, Organic Waste Indicators, and Volatile Organic Chemical Contaminants and Their Predicted Effects Potential in Wadeable Southeastern USA Streams Chemical-Gene and Chemical-Pathway Interactions Predicted for Chemicals Detected in the USGS-USEPA National Streams Pilot Study Based on Effects Data in the Comparative Toxicogenomics Database (CTD) Concentrations of Pharmaceutical Contaminants and Their Predicted Effects from a Multi-Regional Assessment of Wadeable USA Streams, 2014-2017 Concentrations of Pesticides, Pharmaceuticals, Organic Waste Indicators, and Volatile Organic Chemical Contaminants and Their Predicted Effects Potential in Wadeable Southeastern USA Streams Concentrations of Pharmaceutical Contaminants and Their Predicted Effects from a Multi-Regional Assessment of Wadeable USA Streams, 2014-2017 Chemical-Gene and Chemical-Pathway Interactions Predicted for Chemicals Detected in the USGS-USEPA National Streams Pilot Study Based on Effects Data in the Comparative Toxicogenomics Database (CTD)