Filters: Tags: vaccination (X) > Categories: Data (X)

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Serology, survival, and detection of rabies data from vaccination trials in the common vampire bat (Desmodus rotundus) using a recombinant raccoon poxvirus-vectored mosaic rabies vaccine candidate This data set provides biological information from of a captive colony of common vampire bats (wild-caught and born in captivity) that were part of an experimental study on vaccination. It includes results obtained from different assays: RT-PCR, serum neutralization, Rabies direct-fluorescent antibody test, performed periodically during the study (Sep 2018 – May 2020). Categories: Data; Types: Map Service, OGC WFS Layer, OGC WMS Layer, OGC WMS Service; Tags: Rabies, San Luis Potosi, Mexico, Serology, USGS National Wildlife health Center, Madison, WI, USA, USGS Science Data Catalog (SDC), All tags... Wildlife Disease, biota, shedding, survival, vaccination, vaccine treatment, vampire bats, wildlife disease, Fewer tags Virally-vectored vaccine candidates against white-nose syndrome induce anti-fungal immune response in little brown bats (Myotis lucifugus) White-nose syndrome (WNS) caused by the fungus, Pseudogymnoascus destructans (Pd) has killed millions of North American insect-eating bats. Currently, methods to prevent the disease are limited. We conducted two trials to assess potential WNS vaccine candidates in wild-caught Myotis lucifugus. In a pilot study, we immunized bats with one of four vaccine treatments or PBS as a control and challenged them with Pd upon transfer into hibernation chambers. Bats in one vaccine-treated group, that received raccoon poxviruses (RCN) expressing Pd calnexin (CAL) and serine protease (SP), developed WNS at a lower rate (1/10) than other treatments combined (14/23), although samples sizes were small. The results of a second... Categories: Data; Tags: Madison, Wisconsin, USGS National Wildlife Health Center, USGS Science Data Catalog (SDC), Wildlife Disease, bats, All tags... biota, vaccination, white-nose syndrome, Fewer tags Viral loads, histology, and adverse events in transgenic mice after passive transfer of serum from black-footed ferrets (Mustela nigripes) used to assess the anti-viral efficacy of a subunit SARS-CoV-2 vaccine candidate This data set provides biological information from of a captive study of transgenic mice that received either passive serum transfers from black-footed ferrets (BFFs) that were vaccinated against SARS-CoV-2 or BFFs that were unvaccinated, or a monoclonal antibody against SARS-CoV-2 or lastly a placebo. After these treatments mice were challenged with SARS-CoV-2. The data included here have viral loads in the lungs of treated mice, as well as histological results from various tissues collected at the end of the study. Categories: Data; Tags: Passive serum transfer, SARS-CoV-2, USGS National Wildlife Health Center, Madison, WI, USGS Science Data Catalog (SDC), Wildlife Disease, All tags... biota, black-footed ferrets, experimental challenge, immunogenicity and susceptibility, mustelids, pathology, vaccination, viral loads, Fewer tags